长时间坐着减轻皮肤反应性高血压,同时改善静脉动脉反射,交替暴露于冷和热的环境不会调节这些反应

相关实验视频

Updated: Sep 17, 2025

08:21

Author Spotlight: A Pharmacodissection Approach to Uncover Mechanisms in Cardiovascular Disease Risk Populations

Published on: July 21, 2023

1.5K

Kaname Tagawa¹, Yudai Tomita¹, Takeshi Nishiyasu^1,2

¹Institute of Health and Sport Sciences, University of Tsukuba, Tsukuba, Ibaraki, 305-8574, Japan.

European journal of applied physiology

|July 2, 2025

概括

长时间坐着会损害皮肤的微循环,减少闭塞后反应性高血压 (PORH),但意外地改善了静脉动脉反射 (VAR). 血管功能标志物的这些变化没有受到坐着期间温度波动的影响.

科学领域:

生理学生理学生理学
心血管科学心血管科学
皮肤病学皮肤病学

背景情况:

皮肤微循环受损是心血管疾病的早期指标.
久坐不动行为会对血管功能产生负面影响,并增加心血管风险.
长时间坐着对皮肤微血管功能和潜在干预措施的影响仍然不清楚.

研究的目的:

调查长时间坐着是否会导致皮肤微血管功能障碍.
评估坐着对皮肤血液流动,封闭后反应性高血压 (PORH) 和静脉动脉反射 (VAR) 的影响.
为了确定温度变化是否调节长时间坐着对微血管功能的影响.

主要方法:

十二名健康的年轻人接受了120分钟的坐姿干预.
参与者被交替暴露在冷 (18°C) 和温暖 (35°C) 的温度下,在热中性条件 (25°C) 的对照试验中进行了对照试验.
在坐姿期之前和之后测量了皮肤血流,PORH和VAR.

主要成果:

长时间坐着导致PORH的减少和VAR的改善,无论温度条件如何.
皮肤血流反应随温度而变化,在凉爽时降低,在热时保持稳定.
在温度暴露试验和对照试验之间没有观察到PORH或VAR变化的显著差异.

结论:

长时间坐着会通过降低PORH而对皮肤微循环产生负面影响.
意想不到的是,长时间坐着改善了VAR,这表明了复杂的微血管反应.
坐着时环境温度的波动并没有改变PORH和VAR的观察到的变化.

关键词:

对比器在室温下进行对比.微循环是一种微循环.身体不活动.坐在座位上坐着血管扩张功能血管扩张功能

相关概念视频

01:27

Assessment of the Cardiovascular System III: Palpation

502

Palpation involves feeling the body to evaluate texture, size, consistency, and tenderness for assessing cardiovascular health. The following steps are organized in a head-to-toe order:
Jugular Venous Pressure (JVP) Measurement
Position the patient at a thirty- to forty-five-degree angle or in a semi-fowler's position. Look for the highest point of pulsation in the internal jugular vein and measure the vertical distance to the angle of Loius or sternal angle. A normal JVP is 3-4 cm above...

502

01:17

Veins

6.9K

Veins are an integral part of our circulatory system, serving as the blood vessels that transport blood from all body regions to the heart. They are a network of hollow tubes that carry blood low in oxygen from the body's cells back to the heart for reoxygenation. Veins are crucial for maintaining the body's overall fluid balance and the continuous circulation of blood.
Structure of Veins:
The structure of veins is specifically designed to assist in the low-pressure transportation of...

6.9K

02:45

Responses to Heat and Cold Stress

13.9K

Every organism has an optimum temperature range within which healthy growth and physiological functioning can occur. At the ends of this range, there will be a minimum and maximum temperature that interrupt biological processes.

13.9K

01:26

Varicose Veins I: Introduction

Varicose veins, or varicosities, are abnormally dilated and twisted superficial veins caused by venous valve incompetence. This condition commonly affects the lower extremities, especially the saphenous veins, due to the higher pressure from prolonged standing and walking. However, varicosities can also occur in other areas, such as the esophagus, vulva, spermatic cords, and anorectal region.Etiology and typesPrimary varicose veins, often idiopathic, are more common in women due to inherent...

01:43

Thermosensation

31.8K

Peripheral thermosensation is the perception of external temperature. A change in temperature (on the surface of the skin and other tissues) is detected by a family of temperature-sensitive ion channels called Transient Receptor Potential, or TRP, receptors. These receptors are located on free nerve endings. Those detecting cold temperatures are closer to the surface of the skin than the nerve endings detecting warmth. These thermoTRP channels, while temperature selective, have relatively...