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葡萄糖胺激活肠道P-糖蛋白,抑制药物吸收

Qinghua Wu1, Qing Wang2, Xiaohong Luo3

  • 1College of Pharmaceutical Sciences, Southwest University, Chongqing, 400715, China.

Nature communications
|July 2, 2025
PubMed
概括

葡萄糖胺 (GlcN) 快速激活P-glycoprotein (P-gp) 药物流量,而不会改变表达,为急性中毒提供快速解药. 这种P-gp激活有助于排出毒素并维持细胞平衡.

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