在阿布扎比的一项基于人口的队列研究中,2型糖尿病的发生率和预测因素

相关实验视频

Updated: Sep 17, 2025

06:46

A High-Throughput Multiplexed Screening for Type 1 Diabetes, Celiac Diseases, and COVID-19

Published on: July 5, 2022

2.9K

Latifa Mohammad Baynouna AlKetbi^1,2, Rudina AlKetbi³, Mariam Saif AlShamsi⁴

¹Abu Dhabi Healthcare Services, Seha Clinics, Abu Dhabi, United Arab Emirates. Latifa.mohammad@gmail.com.

Scientific reports

|July 3, 2025

概括

在阿布扎比,糖尿病 (DM) 患病率很高,包括高HbA1C和吸烟在内的显著风险因素. 一个新的预测模型有助于早期发现和预防糖尿病的策略.

科学领域:

公共卫生公共卫生
流行病学流行病学
内分泌学在内分泌学.

背景情况:

糖尿病 (DM) 是一个重大的全球健康挑战,需要对其决定因素和发病率进行持续监测.
了解DM的趋势对于有效的风险因素识别和未来的医疗保健规划至关重要.

研究的目的:

报告阿布扎比人口中糖尿病患病率和发病率.
确定显著的风险因素,并开发新发糖尿病的预测模型.
分析糖尿病前期的决定因素及其与年龄和性别的关系.

主要方法:

一个回顾性队列研究 (阿布扎比风险研究 - ADRS) 涉及8699名参与者,平均随访时间为9.2年.
考克斯回归分析以确定决定因素并构建糖尿病预测模型.
对糖尿病和糖尿病前期的流行,发病率和风险因素的分析.

主要成果:

糖尿病患病率增加至28.5% (25.3%的女性,31.9%的男性).
在12年内,糖尿病的总发病率为7.4%,其中较高的HbA1C,吸烟和eGFR是显著的预测因素.
糖尿病前期的决定因素包括较高的DBP,胆固醇,RBS,BMI,年龄和较低的HDL;性别和吸烟并不重要.

结论:

阿布扎比的糖尿病患病率仍然很高,累计糖尿病前期和糖尿病率的增加令人担忧.
一个经过验证的预测模型 (c-统计值0.837) 可以为预防糖尿病提供临床实践的信息.
专注于确定风险因素的公共卫生战略对于管理日益增长的糖尿病负担至关重要.

关键词:

影响影响影响影响群组研究是一项群组研究.糖尿病糖尿病糖尿病预测模型的预测模型风险因素风险因素

相关概念视频

01:22

Diabetes Mellitus: Type 2 and Gestational

3.0K

Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...

3.0K

01:15

Diabetes: Symptoms, Diagnosis, and Complications

706

For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...

706

01:22

Diabetes Mellitus: Overview and Type I Subtype

3.3K

Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...

3.3K

01:20

Pathophysiology of Diabetes

1.2K

Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...

1.2K

01:36

Carbohydrate Metabolism

11.8K

Carbohydrates are polymers composed of molecules containing atoms of carbon, hydrogen and oxygen. One gram of carbohydrate can provide four kilo-calories of energy, which makes it the most efficient instant energy source.
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...

11.8K

01:30

Coronary Artery Disease I: Introduction

Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...