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Updated: Sep 17, 2025

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尽管通过mTOR信号传递和化氧化,SMRT枯竭的常规DC保持了炎症,尽管糖解水平较低,但仍通过mTOR信号传递和化氧化维持炎症

Kaushik Sen1,2, Rashmirekha Pati1, Gyan Prakash Mishra1

  • 1Immunogenomics & Systems Biology Lab, Institute of Life Sciences (ILS), Bhubaneswar, Odisha, 751023, India.

npj metabolic health and disease..
|July 3, 2025
PubMed
概括

树突细胞中SMRT的损失通过改变免疫细胞代谢引起炎症,这与目前的理解相反. 向酸盐氧化和mTOR途径抑制了这种炎症,为自身免疫性疾病提供了新的治疗途径.

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