美国心脏协会生活必需8分和认知功能之间的关联:一个横截面的NHANES研究
Jiuyang Sun1,2, Xinyu Tu1,2, Shuwei Wang1,2
1Department of neurology, Xinhua Hospital, Shanghai Jiao tong University School of Medicine, No.1665 Kongjiang Rd, Shanghai, China.
BMC geriatrics
|July 3, 2025
概括
通过生活必需8 (LE8) 保持理想的心血管健康与更好的认知功能有关. 更高的LE8分数与更好的认知测试分数和自我报告的认知表现相关.
科学领域:
- 心血管健康 心血管健康
- 神经科学是一个神经科学.
- 公共卫生 公共卫生
背景情况:
- 早期痴呆症诊断具有挑战性,晚期干预的有效性有限.
- 生活必需品8 (LE8) 是一种潜在的认知衰退风险因素.
- 探索LE8与认知表现之间的关联对于预防策略至关重要.
研究的目的:
- 为了研究生命的基本8 (LE8) 评分和认知表现之间的关联.
- 区分LE8对客观认知测试成绩和主观认知表现的影响.
主要方法:
- 使用了2011-2014年的NHANES数据.
- 通过认知测试的Z分和自我报告的认知问题来评估认知表现.
- 采用多变量回归和受限制的立方支线模型来分析LE8关联.
主要成果:
- 在LE8分数和认知测试分数和主观认知表现之间观察到正线性关联.
- LE8得分显示了与认知测试得分的J形剂量反应关系.
- LE8预测客观认知测试比主观认知表现更有效,身体活动,尼古丁暴露,血脂和血糖是重要因素.
结论:
- LE8得分显示了与认知测试得分和主观认知表现的显著线性关联.
- 与主观认知功能相比,LE8更好地预测客观认知功能.
- LE8指标,特别是身体活动,是维持认知健康的关键指标.
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