老年癌症患者的肉类,营养状况,身体功能和生活质量之间的关系:路径分析
Liyi Wang1,2,3, Xuejun Dai1,2, Jiao Ai1,2,3
1Cancer Prevention and Treatment Institute of Chengdu, Department of Oncology, Chengdu Fifth People's Hospital, Chengdu, 611130, China.
BMC geriatrics
|July 3, 2025
概括
肉类和营养不良显著影响老年癌症患者的生活质量,身体功能作为关键调解者. 早期干预对于改善结果至关重要.
科学领域:
- 老年学是一门学科.
- 在瘤学瘤学.
- 营养科学 营养科学
背景情况:
- 麻症是老年癌症患者中普遍存在的疾病,通常与不良健康结果有关.
- 了解萨科佩尼亚,营养状况,身体功能和生活质量之间的相互作用对这个人群至关重要.
研究的目的:
- 研究老年癌症患者的肉类和生活质量 (QOL) 之间的关联.
- 检查营养状况和身体功能的介导作用在肉症-QOL关系中的作用.
- 为了探索sarcopenia,营养状况和身体功能之间的复杂相互作用.
主要方法:
- 一项涉及275名老年癌症患者的横截面研究.
- 根据EWGSOP2标准评估的肉类;根据NRS-2002,白蛋白,白蛋白前,BMI评估营养状况.
- 通过6MWD,步行速度,TUG测量的身体功能; EORTC QLQ-C30的QOL.
- 用于数据分析的结构方程建模 (SEM).
主要成果:
- 萨科佩尼亚,营养状况和身体功能共同解释了54%的QOL变异.
- 确定了重要的途径:sarcopenia → 营养状况 → QOL (22.0%),sarcopenia → 身体功能 → QOL (17.07%),和sarcopenia → 营养状况 → 身体功能 → QOL (6.09%).
结论:
- 肉,营养状况和身体功能与老年癌症患者的QOL有显著的联系.
- 身体功能显著调解了sarcopenia和QOL之间的关系,以及营养状况和QOL之间的关系.
- 建议针对萨科佩尼亚,营养和身体功能进行全面的个性化干预,以提高患者的QOL和结果.
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