在患有PDAC的老年患者中,胰腺手术是安全的
Yueming Zhang1, Siyang Han1, Yaolin Xu1
1Department of Pancreatic Surgery, Cancer Center, Department of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.
BMC geriatrics
|July 3, 2025
概括
胰腺手术对于患有胰腺管腺癌 (PDAC) 的老年患者来说是安全的,只要提供全面的手术前评估和术后护理. 结果与年轻患者相似,即使老年人的炎症营养状况较差.
科学领域:
- 在瘤学瘤学.
- 老年人手术是一门老年人手术.
- 外科手术的结果
背景情况:
- 在老年人群中,胰腺管道腺癌 (PDAC) 诊断正在增加.
- 与年轻同行相比,老年PDAC患者通常接受不理想的治疗.
- 对老年PDAC患者的手术干预的安全性进行了辩论.
研究的目的:
- 评估在老年人与PDAC的非老年患者中彻底切除的安全性和结果.
- 为了比较年龄组之间的手术相关因素和术后并发症.
- 评估炎症营养状况对老年和非老年PDAC患者手术结果的影响.
主要方法:
- 对892名经过彻底切除的PDAC患者 (2012-2021) 的回顾性分析.
- 患者分为非老年人 (<70岁) 和老年人 (≥70岁) 组.
- 临床病理学因素,手术结果和术后并发症的比较;炎症营养状况的子组分析.
主要成果:
- 老年患者呈现较早的AJCCT和N阶段,但ASA等级较高.
- 老年患者的炎症标志物和营养状况较差.
- 术后并发症的发生率相似,除了胃空气的延迟;较差的炎症营养状况与更复杂的手术相关,特别是在非老年患者中.
结论:
- 在经验丰富的中心,胰腺手术对老年PDAC患者是安全的.
- 综合性手术前评估和细致的术后护理对于优化结果至关重要.
- 年龄本身不应该是PDAC患者手术干预的禁忌.
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