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Synthesis and Regulation of Thyroid Hormones01:20

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Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
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As a nurse, it is vital to understand the factors affecting body temperature to monitor variations and effectively evaluate deviations from regular.
Factors may  include:
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The thyroid hormone (TH) plays a pivotal role in the intricate orchestration of physiological processes, exerting profound effects on development, metabolism, and homeostasis throughout different life stages.
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Here are the steps to accurately measure oral temperature using an electronic thermometer:
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Take the thermometer out of the charging unit, switch it on, and wait for the ready sign.
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Body temperature reflects the equilibrium between heat production and heat loss within the body. Most heat is generated by metabolically active tissues, particularly the liver, heart, brain, kidneys, and endocrine organs. At rest, skeletal muscles contribute 20–30% of total heat production, but during vigorous exercise, this can increase up to 30–40 times.
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相关实验视频

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Author Spotlight: In Vivo Assessment of Thyroid Hormone Disruption Using the THAI Mouse Model
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环境温度对甲状腺功能参数的影响:每日一级小组研究

Tao Wang1, Hailin Ma1, Zhaoqing Jin1

  • 1The 949th Chinese PLA Hospital, 219 Tuanjie Road, Altay, 836500, Xinjiang, China.

BMC public health
|July 3, 2025
PubMed
概括

极低的环境温度显著影响甲状腺功能,增加了自由三甲状腺素 (FT3) 和自由甲状腺素 (FT4) 的水平. 建议采取寒冷天气的保护措施,特别是对于甲状腺疾病患者.

关键词:
DLNM DLNM DLNM DLNM DLNM 在线环境温度极低的环境温度非常低.专家小组研究小组研究甲状腺功能 甲状腺功能

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科学领域:

  • 环境健康 环境健康
  • 内分泌学 在内分泌学.
  • 流行病学 流行病学

背景情况:

  • 对于甲状腺功能的季节性影响是已知的,但极端寒冷和温度滞后的具体影响尚未得到充分理解.
  • 调查非线性和滞后温度影响对于寒冷时期的公共卫生至关重要.

研究的目的:

  • 分析极低环境温度与甲状腺功能参数之间的非线性和滞后关联.
  • 为了识别特定的甲状腺激素的变化,以应对寒冷的暴露.

主要方法:

  • 一个小组研究设计,利用来自中国阿尔泰市1237人的数据 (2020-2023年).
  • 使用分布式滞后非线性模型 (DLNMs) 的混合效应建模来分析五个甲状腺功能参数.
  • 分析包括与8.5°C的基准温度进行比较.

主要成果:

  • 在-20°C时,与基准温度相比,观察到自由三甲状腺素 (FT3) 和自由甲状腺素 (FT4) 的显著增加.
  • 升高的温度 (20°C至29°C) 与增加的总甲状腺素 (TT4) 和减少的FT4.4相关.
  • 亚组分析显示,女性的TT4增加更大,甲状腺疾病患者的TT4,FT4和FT3增加更明显.

结论:

  • 非常低的环境温度显然会影响甲状腺功能,改变关键激素水平.
  • 建议在寒冷的天气中采取保护措施,以保持甲状腺的稳定性.
  • 易受伤害的群体,特别是甲状腺疾病患者,可能需要加强对暴露于寒冷的预防措施.