沉默的威胁:PM2.5暴露对围产期并发症和新生儿后果的影响
Fei Li1, Xiaolei Liu2, Shuo Gong1
1Center for Reproductive Medicine, The First People's Hospital of Shangqiu, Clinical College Affiliated to Xinxiang Medical University, Shangqiu, Henan Province, China.
BMC pregnancy and childbirth
|July 3, 2025
概括
暴露于细颗粒物 (PM2.5) 与更高的妊娠高血压率和新生儿出生体重较低有关. 空气质量应该是产前护理的一个关键考虑因素,以减轻这些风险.
科学领域:
- 环境健康 环境健康
- 产科和妇科 产科和妇科
- 新生儿医学 新生儿医学
背景情况:
- 细颗粒物 (PM2.5) 是已知的健康风险,但其对围产期并发症和新生儿后果的影响需要进一步调查.
- 了解PM2.5暴露与怀孕结果之间的关系对于改善母婴保健策略至关重要.
研究的目的:
- 调查暴露于细颗粒物 (PM2.5) 和围产期并发症和新生儿结局之间的关联.
- 分析不同程度的PM2.5暴露与不良怀孕和分娩结果之间的相关性.
主要方法:
- 在2018年2月至2022年12月期间,从两个医院回顾分析了13,828名患者记录.
- 患者根据分娩方法 (阴道或剖腹产) 和PM2.5暴露水平 (<50μg/m3,50-100μg/m3,>100μg/m3) 分类.
- 包括后勤回归和通用添加模型 (GAM) 在内的统计分析被用来评估PM2.5暴露与结果之间的关系.
主要成果:
- 在阴道和剖腹产中,PM2.5暴露与妊娠高血压的增加显著相关 (p < 0.001).
- 在所有分娩方式中,较高的PM2.5水平与较低的出生体重相关 (p < 0.001).
- 在剖腹产分娩组中观察到较高的PM2.5暴露率 (p = 0.006) 增加了橄水的发病率.
结论:
- 增加的PM2.5暴露与妊娠高血压增加和出生体重减少有显著的相关性.
- 研究结果表明,PM2.5暴露对围产期结局的影响存在潜在的非线性关系和值.
- 产科医生应将空气质量监测和意识纳入产前护理协议,以应对PM2.5相关的风险.
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