为预测口腔癌老年患者手术后妄想症开发和验证名录模型:一项回顾性研究
Chen Ying1, Liu Xiaona2, Zhang Aili3
1Oral and Maxillofacial Head and Neck Oncology Surgery Ward II, Nanjing Stomatological Hospital, Affiliated Hospital of Medical School, Institute of Stomatology, Nanjing University, Nanjing, China. chenyingYZU@163.com.
BMC oral health
|July 3, 2025
概括
这项研究开发了一种名谱,用于预测老年口腔癌患者的手术后痴呆症 (POD). 该模型有效地识别了关键风险因素,有助于临床评估和患者护理.
科学领域:
- 在瘤学瘤学.
- 老年病的医生 老年病的医生
- 麻醉学 麻醉学
- 精神病学是一个精神病学.
背景情况:
- 手术后痴呆症 (POD) 在接受口腔癌手术的老年患者中是一个重大问题.
- 准确的风险预测对于及时干预和改善患者结果至关重要.
研究的目的:
- 开发和验证一个动态的诺莫格拉姆模型,用于预测口腔癌老年患者的POD风险.
- 在这个特定的患者群体中确定与POD相关的关键风险因素.
主要方法:
- 一项涉及359名老年口腔癌患者的回顾性研究.
- 使用最小绝对收缩和选择操作员 (LASSO) 回归来进行变量选择.
- 使用后勤回归开发了一个预测模型,并将其视觉化为名ogram.
主要成果:
- 确定了POD的七个显著预测因素:年龄,性别,酒精史,婚姻状况,手术前焦虑,睡眠障碍和重症监护室停留时间.
- 诺米图表显示出高的预测准确性,在训练组的曲线下面积 (AUC) 为0.82,在验证组为0.84.
- 决策曲线分析证实了预测模型的良好的临床效用.
结论:
- 在老年口腔癌患者中成功开发和验证了一种基于诺莫格拉姆的POD新型预测模型.
- 该工具为医生提供了一种快速有效的方法来评估POD风险,促进主动管理.
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