饮食炎症指数和中年和老年代谢综合征患者的死亡率
Xiangmei Li1, Lei Liu2, Xing Li1
1Department of Health Care Center, First Affiliated Hospital of Xinjiang Medical University, Ürümqi, China.
Diabetology & metabolic syndrome
|July 3, 2025
概括
较高的饮食炎症评分 (DII) 与代谢综合征 (MetS) 的老年人死亡风险增加有关. 采用抗炎饮食可能会降低心脏代谢性死亡风险.
科学领域:
- 营养科学 营养科学
- 心血管健康 心血管健康
- 老年学是指老年学的学科.
背景情况:
- 代谢综合征 (MetS) 在老年人中增加了心血管疾病和死亡风险.
- 饮食炎症指数 (DII) 衡量饮食的炎症潜力.
- DII与MetS患者的死亡率之间的联系尚未得到充分证实.
研究的目的:
- 调查DII与中年和老年MetS患者的全因和心血管死亡率之间的关联.
主要方法:
- 使用NHANES数据 (2005-2016) 对7,143名MetS患者 (≥40岁) 的回顾性队列研究.
- 使用联合临时声明标准诊断的MetS.
- 从28个食物/营养素参数计算DII;使用卡普兰-梅尔曲线和考克斯回归分析生存率;使用限制立方探讨剂量反应.
主要成果:
- 较高的DII四分位数与较低的生存率相关.
- 每一个DII单位的增加都与更高的全因死亡率 (HR=1.052) 和心血管死亡率 (HR=1.157) 相联系.
- 与最低四分位数相比,最高的DII四分位数显示所有原因 (HR=1.289) 和心血管死亡率 (HR=1.817) 的风险显著增加.
结论:
- 较高的DII分数独立地与MetS患者的死亡率增加有关.
- 抗炎饮食可能是一个具有成本效益的,非药物战略,以减少高心脏代谢风险的老年人群的死亡率.
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