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Updated: Sep 17, 2025

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通过抑制BNIP3介导的线粒细胞衰变,CDK12无活化减轻了前列腺癌的进展

Mengjun Huang1, Hanqi Lei1, Tongyu Tong1

  • 1Department of Urology, Pelvic Floor Disorders Center, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, China.

Cell proliferation
|July 3, 2025
PubMed
概括

抑制CDK12会损害前列腺癌细胞中的髓,提高对恩扎胺的敏感性. 这揭示了针对CDK12-BNIP3-mitophagy轴的新治疗策略,以克服耐药性.

关键词:
在BNIP3中,BNIP3是BNP3.在CDK12中,CDK12就是CDK12.恩扎胺的治疗方法线粒细胞衰变 (mitophagy) 是一种神经衰变的过程.前列腺癌是前列腺癌.

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