代谢表型和个性化营养可以帮助我们的饮食更可持续吗?
Katie P Davies1, Eileen R Gibney1, Aifric M O'Sullivan1
1UCD Institute of Food and Health, School of Agriculture and Food Science, University College Dublin, Belfield Dublin 4, Ireland.
The Proceedings of the Nutrition Society
|July 3, 2025
概括
可持续饮食有益于健康和地球. 个性化营养,使用代谢表型,可以优化个人对健康饮食模式的反应.
科学领域:
- 营养科学 营养科学
- 环境健康 环境健康
- 个性化医疗是个性化的医疗.
背景情况:
- 可持续饮食为个人健康和地球福祉提供了共同利益.
- 现有的研究将较低的环境影响饮食与改善的健康结果联系起来.
- 干预研究对于定义最佳饮食变化和了解各种各样的个人反应至关重要.
研究的目的:
- 在可持续健康饮食的背景下,审查个人间的变化和表型反应.
- 探索代谢表型化用于个性化营养的应用.
- 确定未来对整体饮食变化和可持续饮食模式的研究需求.
主要方法:
- 文献综述检查了个体间的变化和表型反应.
- 对饮食干预的随机对照试验的分析.
- 探索代谢表型化 (metabotyping) 方法来对个人进行分组.
主要成果:
- 对饮食变化和改善饮食质量的生理反应在个体之间有很大差异.
- 代谢表型可以识别那些倾向于对特定饮食干预做出反应的个体.
- 根据代谢表型量身定制饮食建议显示了改善健康和饮食质量的潜力.
结论:
- 了解个人之间的差异是推动可持续健康饮食的关键.
- 代谢表型化为可持续的饮食框架内个性化营养提供了一个有希望的战略.
- 需要进一步的研究来解决整体饮食变化和个性化的可持续营养的复杂性.
更多相关视频
相关概念视频
Background and Environment Affect Phenotype
6.7K
Although the genetic makeup of an organism plays a major role in determining the phenotype, there are also several environmental factors, such as temperature, oxygen availability, presence of mutagens, that can alter an organism’s phenotype.
An example of how genetic background affects phenotype can be seen in horses. The Extension gene in horses is responsible for their coat color. A wild-type gene (EE) produces black pigment in the coat, while a mutant gene (ee) produces red pigment. A...
An example of how genetic background affects phenotype can be seen in horses. The Extension gene in horses is responsible for their coat color. A wild-type gene (EE) produces black pigment in the coat, while a mutant gene (ee) produces red pigment. A...
6.7K
Combination Therapies and Personalized Medicine
5.1K
Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
5.1K
Human Genetics
738
Human genetics provides a profound framework for understanding the interplay between genetic predispositions and human psychology. At the heart of this discipline lies the study of how genes influence physical traits, behaviors, and susceptibility to diseases. Each person carries a unique genetic code that subtly or significantly shapes their psychological and behavioral landscape.
The complex relationship between genetics and psychology is observable through common biological components such...
The complex relationship between genetics and psychology is observable through common biological components such...
738
Overview of Metabolism
32.1K
Living cells constantly carry out various chemical reactions which are necessary for their proper functioning. These reactions are interlinked to one another via multiple pathways. The collection of these chemical reactions is known as metabolism.
Plant Metabolism
Sunlight, the primary source of energy in plants, is first absorbed by the chlorophyll pigments present in their leaves. Plants then use this energy to carry out photosynthesis, where water is oxidized into oxygen and carbon dioxide...
Plant Metabolism
Sunlight, the primary source of energy in plants, is first absorbed by the chlorophyll pigments present in their leaves. Plants then use this energy to carry out photosynthesis, where water is oxidized into oxygen and carbon dioxide...
32.1K
Introduction to Metabolism
440
Metabolism encompasses all biochemical reactions in a living organism, facilitating both the breakdown and synthesis of biomolecules. These metabolic processes are categorized into catabolic and anabolic pathways, which operate in a coordinated manner to ensure energy balance and cellular function.Catabolic Pathways and Energy ReleaseCatabolic pathways involve the breakdown of complex macromolecules such as carbohydrates, lipids, and proteins into smaller structures like monosaccharides, fatty...
440
Regulation of Metabolism
9.9K
Cellular needs and conditions vary from cell to cell and change within individual cells over time. For example, the required enzymes and energetic demands of stomach cells are different from those of fat storage cells, skin cells, blood cells, and nerve cells. Furthermore, a digestive cell works much harder to process and break down nutrients during the time that closely follows a meal compared with many hours after a meal. As these cellular demands and conditions vary, so do the amounts and...
9.9K


