振荡计血压测量:对面积振荡图和高度振荡图的建模和分析
Vishaal Dhamotharan1, Hao-Min Cheng2, Shih-Hsien Sung2
1Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA, United States.
Frontiers in physiology
|July 3, 2025
概括
对于振荡计血压 (BP) 测量的新数学模型准确地表示振荡形状. 这些模型,特别是面积振荡图,为更精确的BP读数提供了更好的洞察力.
科学领域:
- 生物医学工程 生物医学工程
- 心血管生理学心血管生理学
- 医疗器械 医疗器械 医疗器械
背景情况:
- 振荡计是非侵入性血压 (BP) 测量的主要方法.
- 传统分析依赖于振荡高度与袖口压力,称为高度振荡图.
- 振荡计振荡的形状也随着袖口压力而变化,提供了潜在的更多信息.
研究的目的:
- 开发数学模型描述振荡形状和高度变化在振荡计.
- 用患者数据分析这些模型,以评估它们的准确性和实用性.
- 为了研究提高血压测量准确度的潜力.
主要方法:
- 利用了来自109名不同患者的振荡计手臂袖压力和侵入性手臂血压波形.
- 开发了一个对振荡区域与袖口压力的分析模型 ("区域振荡图").
- 使用患者数据评估了面积振荡图模型和之前的高度振荡图模型.
主要成果:
- 面积和高度振荡图模型都显示出与患者数据的良好匹配.
- 面积振荡图模型实现了6.9%±0.3%的适配误差.
- 高度振荡图模型的适配误差为8.7%±0.4%;粘性弹性和非线性影响了模型的适配.
结论:
- 开发的面积振荡图模型和现有的高度振荡图模型有效地复制患者的振荡图.
- 这些经过验证的模型有望提高振荡计血压测量的准确性.
- 进一步细化可能会解释系统的非线性和粘弹性特性.
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