使用双能量CT定量参数,区分肺栓塞与对比积累诱导的光束硬化工件
Qingle Wang1,2,3, Heqing Wang4, Chong Lin4
1Department of Radiology, Zhongshan Hospital, Fudan University, Shanghai, China.
双能量CT (DECT) 的定量参数可以在CTPA扫描期间区分光束硬化器件 (BHA) 和肺栓塞 (PE). 90 keV和100 keV的虚拟单能图像对于诊断特别有价值.
科学领域:
- 放射学 放射学是一门学科.
- 医疗成像医学成像
- 诊断技术 诊断技术
背景情况:
- 计算机断层扫描肺血管造影 (CTPA) 可能会受到光束硬化工件 (BHA) 的影响,这些工件是由上 vena cava 对比引起的.
- 这些文物可能会阻碍肺栓塞 (PE) 的准确诊断.
研究的目的:
- 为了评估双能计算断层扫描 (DECT) 的诊断实用性,量化参数.
- 在CTPA检查中,将肺栓塞 (PE) 与光束硬化器件 (BHA) 区分开来.
主要方法:
- 对68名接受DE-CTPA治疗的PE患者进行了回顾性分析.
- 量化参数的测量:霍恩斯菲尔德单位 (HU) 曲线的斜率 (Slope),虚拟单能图像 (VMIs) 的CT值 (40100 keV),正常化度 (NIC) 和正常化有效原子数 (NEffZ).
- 在正常动脉,人工物区域和栓塞区域的参数比较.
主要成果:
- 定量参数 (HU,NIC,NEffZ,Slope) 在正常动脉中最高,在人造物中中间,在栓塞中最低 (P<0.05).
- 参数有效地区分了人工物和栓塞 (AUC>0.80),HU在100 keV时显示了最高的AUC (0.963).
- 组合参数提高了差异化准确性,特别是在正常与人工物和正常与栓塞检测方面.
结论:
- 从DECT衍生出的定量参数可以在上腔静脉中识别BHA.
- 90 keV和100 keV的虚拟单能图像,以及它们的HU测量,对于区分文物和PE非常有价值.
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