饮食习惯和阴道环境:可以预期有益的影响吗?
Marielle Ezekielle Djusse1,2, Federica Prinelli3, Tania Camboni3
1Section of Microbiology, Department of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum - University of Bologna, Bologna, Italy.
Frontiers in cellular and infection microbiology
|July 3, 2025
概括
饮食习惯显著影响阴道健康. 减少动物蛋白和酒精摄入量,同时增加烯酸,促进有益的阴道微生物群,其中占主导地位的是保护性乳酸菌种.
科学领域:
- 生殖健康 生殖健康
- 微生物组研究 微生物组研究
- 营养科学 营养科学
背景情况:
- 健康的阴道微生物群,通常由乳酸菌种占主导地位,对于生殖年龄妇女的健康至关重要.
- 影响阴道微生物群组成的因素越来越多地被研究,但饮食影响仍然未得到充分研究.
研究的目的:
- 研究年轻女性的宏观营养素摄入量和阴道微生物群组成之间的关联.
- 为了确定可能促进或破坏阴道微生物平衡的特定饮食模式.
主要方法:
- 对113名生育年龄妇女进行的横截面研究.
- 通过16S rRNA基因分析确定的阴道细菌社区状态类型 (CST).
- 使用1H-NMR光谱分析的阴道代谢概况.
- 通过经过验证的食物频率问卷评估的饮食摄入量.
主要成果:
- 增加的动物蛋白和酒精消费与失生性阴道微生物群 (CST IV) 和增加的Gardnerella spp.相关. 和Ureaplasma spp. 这种疾病.
- 更高的阿尔法-烯酸摄入量与从CST III (Lactobacillus iners-dominant) 和增加Lactobacillus crispatus丰度的有益转移有关.
- 特定的代谢物,如4-基乳酸和氨基酸与Lactobacillus crispatus有关.
- 碳水化合物,植物蛋白质,纤维和粉与Gardnerella spp.有负相关性.
结论:
- 特定的饮食选择,包括减少酒精和动物蛋白摄入量以及增加酸消费,对阴道环境产生积极影响.
- 这些饮食修改支持由有益的乳酸菌种占主导地位的微生物群,这对于保持阴道健康至关重要.
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