在患有代谢功能障碍相关的脂肪肝病患者中,妇产炎和内分泌调节之间的相关性:一个横截面研究
Ming-Huang Zhang1, Ning Meng2, Kang-Hui Zhang1
1Department of Thyroid and Breast Surgery, Affiliated Hospital of Hangzhou Normal University, Hangzhou 310015, Zhejiang Province, China.
World journal of hepatology
|July 3, 2025
概括
妇产 (GYN) 在与代谢功能障碍相关的脂肪肝疾病 (MASLD) 患者中更为普遍,随着疾病的严重程度而增加. 早期的妇产科医生检测可能标志着严重的代谢问题,有助于早期干预.
科学领域:
- 内分泌学 在内分泌学.
- 肝病学 肝病学是一种肝病学.
- 代谢综合征研究 代谢综合征研究
背景情况:
- 与代谢功能障碍相关的脂肪肝疾病 (MASLD) 是与代谢综合征相关的日益严重的健康问题.
- 妇产 (GYN),以男性乳腺组织的增殖为特征,与荷尔蒙失衡有关.
- 关于妇产科医生患病率及其在MASLD患者群体中的相关性,研究有限.
研究的目的:
- 为了确定诊断为MASLD的患者中妇产科医生患病率.
- 在MASLD患者中确定与GYN相关的临床特征.
- 通过ROC曲线分析评估妇产科医生性激素的预测价值.
主要方法:
- 一项涉及997名MASLD患者的横截面研究,这些患者接受了乳房超声波检测GYN.
- 收集人体测量数据,肝功能测试,葡萄糖,脂质,性激素 (雌激素,雄激素) 和病史.
- 使用SPSS版本27和R软件 (4.3.1版本) 的统计分析.
主要成果:
- 妇产科医生患病率随着MASLD的严重程度显著增加 (27.6%轻度,33.5%中度,58%严重).
- 妇产科医生患者年龄较大,表现出较高的雌激醇水平和雌激素与雄激素的比率,较低的雄激素水平.
- 和雌激醇的组合模型显示,在MASLD患者中预测GYN的诊断价值很高.
结论:
- 在MASLD患者中GYN的存在可能表明更严重的潜在代谢异常.
- 早期识别妇产科医生对于及时干预代谢综合征和与MASLD相关的内分泌功能障碍至关重要.
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