嗅觉障碍与体力减弱有关,在COVID-19后24个月
Christoffer Granvik1, Alicia Lind2, Guilherme W F Barros3
1Department of Clinical Microbiology, Umeå University, Umeå, Sweden.
Brain, behavior, & immunity - health
|July 3, 2025
概括
患有嗅觉障碍的COVID-19幸存者经历了长达两年的身体能力减弱. 这项研究表明,嗅觉丧失对所有年龄组的长期身体表现产生影响.
科学领域:
- 神经学 神经学
- 传染性疾病 传染性疾病
- 老年学是一门学科.
背景情况:
- 嗅觉障碍与不良健康结果有关,特别是在老年人中.
- COVID-19已经引起了所有年龄组的嗅觉障碍的关注.
- 后COVID嗅觉功能障碍的长期影响需要调查.
研究的目的:
- 研究COVID-19患者的后急性嗅觉障碍和长期身体能力之间的关联.
- 测试假设,嗅觉受损与COVID-19后体力表现下降的相关性.
主要方法:
- 63名COVID-19患者的前性队列研究.
- 感染后1-3个月使用值查,强度等级和气味识别来评估嗅觉功能.
- 在3,6,12和24个月以1分钟的坐立测试测量身体能力,并使用部分相关性和线性混合模型进行分析.
主要成果:
- 36.5%的参与者在急性后的早期阶段有嗅觉障碍.
- 在所有随访中,嗅觉障碍与身体能力之间发现了显著的负相关性.
- 嗅觉障碍与感染后长达24个月的身体能力下降有关,随着时间的推移,这种关联越来越加强.
结论:
- 在COVID-19患者的早期后急性嗅觉障碍预测24个月后身体能力下降.
- 嗅觉障碍对身体表现的影响超出了老年人群.
- 需要对更大的队列进行进一步的研究,以证实这些关于嗅觉功能障碍和身体能力的发现.
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