相关实验视频

Updated: May 10, 2026

Development and Maintenance of a Preclinical Patient Derived Tumor Xenograft Model for the Investigation of Novel Anti-Cancer Therapies
09:29

Development and Maintenance of a Preclinical Patient Derived Tumor Xenograft Model for the Investigation of Novel Anti-Cancer Therapies

Published on: September 30, 2016

13.9K

案例报告:转移性结直肠癌与ALK-CEP44融合和快速抗药性发展

Silvan Hofmann1, Claudine Egger1, Silke Potthast2

  • 1Department of Internal Medicine, Section of Medical Oncology and Hematology, Spital Limmattal, Schlieren, Switzerland.

Frontiers in oncology
|July 3, 2025
PubMed
概括

这项案例研究突出了转移性结直肠癌 (CRC) 中罕见的ALK-CEP44融合. 尽管最初对ALK抑制剂alectinib有反应,但该患者发生了耐药性突变,这强调了需要在CRC治疗中进行综合分析的必要性.

关键词:
发生ALK基因突变.案例报告案例报告结肠直肠癌是什么意思药物耐药性 耐药性 药物耐药性有针对性的治疗.

更多相关视频

A Blood-based Test for the Detection of ROS1 and RET Fusion Transcripts from Circulating Ribonucleic Acid Using Digital Polymerase Chain Reaction10:35

A Blood-based Test for the Detection of ROS1 and RET Fusion Transcripts from Circulating Ribonucleic Acid Using Digital Polymerase Chain Reaction

Published on: April 5, 2018

10.5K
Oncogenic Gene Fusion Detection Using Anchored Multiplex Polymerase Chain Reaction Followed by Next Generation Sequencing09:49

Oncogenic Gene Fusion Detection Using Anchored Multiplex Polymerase Chain Reaction Followed by Next Generation Sequencing

Published on: July 5, 2019

9.7K

相关概念视频

Treatment Resistant Cancers02:56

Treatment Resistant Cancers

Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...