饮食中的碳水化合物摄入量和整体癌症和21种特定部位癌症的风险:一项前性队列研究
Shuhui Chen1, Baojie Hua1, Bin Liu1
1Department of Epidemiology, School of Public Health, Zhejiang Chinese Medical University, Hangzhou, China.
Frontiers in nutrition
|July 3, 2025
概括
食纤维和非自由糖可能会降低癌症风险,而自由糖和糖与癌症风险增加有关. 这项研究探讨了近20万名英国生物银行参与者的碳水化合物摄入量和癌症发病率.
科学领域:
- 营养科学 营养科学
- 在瘤学瘤学.
- 流行病学 流行病学
背景情况:
- 饮食显著影响癌症风险,这是全球主要的死亡原因.
- 对饮食中的碳水化合物与癌症之间的联系进行的全面研究是有限的.
研究的目的:
- 研究饮食碳水化合物摄入量与发展整体癌症和特定部位癌症的风险之间的关联.
- 提供碳水化合物与癌症关系的详细分析,使用大量的潜在队列.
主要方法:
- 一项前性队列研究,涉及来自英国生物银行的194,388名参与者.
- 使用牛津WebQ24小时回忆问卷评估的饮食摄入量.
- 考克斯比例危险模型用于计算癌症发病率的危险比率.
主要成果:
- 食纤维摄入量与整体,食道,结肠直肠,肺和癌的风险降低有关.
- 较高的自由糖摄入量与肺癌和癌的风险增加有关.
- 非自由糖显示整体,结肠直肠和肺癌的风险降低;糖糖摄入增加了肺癌和非霍奇金淋巴瘤风险.
结论:
- 增加食纤维和非自由糖的摄入量可能会降低几种癌症的风险.
- 增加自由糖和糖糖的摄入量与患特定癌症的风险更高有关,可能是由于炎症和氧化应激.
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