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Updated: Jul 29, 2026

Fluorescence-quenching of a Liposomal-encapsulated Near-infrared Fluorophore as a Tool for In Vivo Optical Imaging
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一个双激发比度NIR-II光纳米平台使得高对比度的in vivo成像

Yongchao Liu1,2, Lili Teng1, Bo Zhang1

  • 1State Key Laboratory of New Pharmaceutical Preparations and Excipients, Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of Ministry of Education, College of Chemistry and Materials Science, Hebei University Baoding 071002 China liuyongchao@hnu.edu.cn.

Chemical science
|July 3, 2025
PubMed
概括

研究人员开发了一种新型的双激发比度NIR-II光纳米平台 (DERF-NP),用于改进自我校准成像. 这项技术提高了成像质量和灵敏度,用于跟踪巨细胞极化和淋巴转移等生物过程.

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相关概念视频

Total Internal Reflection Fluorescence Microscopy01:05

Total Internal Reflection Fluorescence Microscopy

Total internal reflection fluorescence microscopy or TIRF is an advanced microscopic technique used to visualize fluorophores in samples close to a solid surface with a higher refractive index, such as a glass coverslip. TIRF only allows fluorophores in proximity to the solid surface to be excited. When light from a medium with a lower refractive index (such as air) hits the glass coverslip at a critical angle, the light undergoes total internal reflection stead of passing through the glass.