帕金森病患者执行功能与双重任务行走之间的关系
Jun-Hong Zhou1, Ray-Yau Wang1, Yo-Tsen Liu2,3,4,5
1Department of Physical Therapy and Assistive Technology, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Frontiers in aging neuroscience
|July 3, 2025
概括
在患有帕金森病 (PwPD) 的人群中,Stroop颜色和文字测试 (SCWT) 显著预测了双重任务行走性能,突出了抑制控制步行的重要性. 这一发现有助于理解和管理PD的步态挑战.
科学领域:
- 神经科学是一个神经科学.
- 运动障碍 运动障碍
- 认知功能 认知功能
背景情况:
- 认知障碍,特别是执行功能障碍,在帕金森病 (PwPD) 中很常见,并可能影响步态.
- 关于PwPD中双重任务步行和执行功能之间的联系的先前研究产生了不一致的结果.
- 执行职能子域对双重任务行走的具体影响仍未得到充分研究.
研究的目的:
- 调查PwPD中双重任务步行和特定执行功能子域之间的相关性.
- 评估不同执行功能子域在PD中对双重任务行走表现的预测能力.
主要方法:
- 一项涉及30名PwPD的横截面研究.
- 在单任务,认知双任务和运动双任务行走条件下进行步行评估.
- 执行功能的评估使用了Trail Making Test (TMT),Stroop Color and Word Test (SCWT) 和数字跨度测试 (DST) 的方法.
主要成果:
- 在双重任务条件下行走速度与TMT Part A和SCWT性能相关.
- 双重任务行走期间的脚步长度与多个执行功能指标有更广泛的相关性.
- 在两种双任务条件下,SCWT是步行速度的唯一有意义的预测器;它还预测了认知双任务中的步伐长度,与运动双任务中的前进数字跨度测试 (DST) 一起.
结论:
- 在PwPD中,SCWT显示了与双重任务步行表现的最强的关联.
- 通过SCWT测量的抑制控制,对于调节帕金森病患者双重任务行走至关重要.
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