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莱索托布塔布特区的结核病治疗坚持和相关因素:一项回顾性队列研究
Motlatsi Rangoanana1, Veranyuy Ngah1, Jacques Lukenze Tamuzi1
1Division of Epidemiology and Biostatistics, Department of Global Health, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.
The Pan African medical journal
|July 3, 2025
概括
在莱索托,结核病治疗的坚持率非常低.
科学领域:
- 公共卫生 公共卫生
- 传染性疾病 传染性疾病
- 流行病学 流行病学
背景情况:
- 莱索托被确定为全球30个结核病 (TB) 负担较高的国家之一.
- 布塔布特区的结核病治疗不良结果高于世卫组织推的标准.
研究的目的:
- 评估Butha-Buthe患者的结核病治疗坚持和抗药模式.
- 为了确定影响结核病治疗坚持的因素,在这个高负担地区.
主要方法:
- 对1320名唾液涂抹阳性或肺外结核病患者的医疗记录的回顾性分析 (2015年1月 - 2020年12月).
- 数据收集包括患者人口统计,结核病类型,治疗阶段和社会支持.
- 使用单变量和多变量逻辑回归分析来确定与治疗坚持相关的因素.
主要成果:
- 总体平均结核病治疗坚持率低至37.20%.
- 与增加坚持相关的因素包括矿工,肺结核病,处于延续阶段,以及从家人,朋友或配偶那里得到支持.
- 年龄较大 (≥60岁) 与粘附性降低有关.
结论:
- 在Butha-Buthe地区,结核病治疗的坚持显著差.
- 在莱索托,迫切需要针对性地制定地区级战略,以提高结核病治疗的坚持率和减轻治疗耐药性.
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