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在CAR-T细胞疗法或干细胞移植后,在家中使用以患者为中心的护理技术:一个潜在的可行性研究
Susan L Moore1,2, Glen J Peterson3, Sarah R Montoya4
1Division of General Internal Medicine, University of Colorado School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, United States.
Frontiers in immunology
|July 3, 2025
概括
数字健康技术 (DHT) 实现了干细胞移植 (SCT) 和CAR T细胞治疗患者的可行远程监测. 这种方法改善了患者的护理感知,并证明了及时干预的潜力.
科学领域:
- 在瘤学瘤学.
- 数字健康数字健康
- 患者监测 患者监测
背景情况:
- 化学疗法和免疫疗法等癌症疗法可能会导致严重的副作用,如发烧性中性质衰竭,神经毒性和细胞因子释放综合征.
- 使用数字健康技术 (DHT) 的远程监控可以改善这些副作用的早期干预,减少并发症和患者负担.
- 目前的患者自主自我评估往往导致在门诊机构的治疗延迟.
研究的目的:
- 评估以患者为中心,技术辅助的远程监测计划的可行性和用户体验,用于接受干细胞移植 (SCT) 或CAR T细胞治疗的患者.
- 评估使用生物识别传感器和聊天机器人进行远程症状报告和健康检查的技术和操作方面.
- 收集患者,护理人员和提供者关于该计划可接受性和对护理质量影响的反.
主要方法:
- 一项试点研究涉及10名接受SCT或CAR T细胞治疗的患者.
- 通过可穿戴生物识别传感器对生命体征进行持续监测.
- 通过双向SMS聊天机器人报告症状和健康检查.
- 虚拟护理中心的工作人员监控了警报,并采取了后续行动.
- 使用调查和采访来评估用户体验.
主要成果:
- 10名患者中有9名成功使用了DHT监测系统.
- 总共产生了219个警报,导致了不同级别的随访,包括对10名患者的临床访问.
- 患者和护理人员报告说,他们感觉得到了更多的照顾,提供者认为护理质量有所改善.
- 用户建议改善信息提供和沟通流程.
结论:
- 基于数字健康技术的远程患者监测对于接受SCT和CAR T细胞治疗的患者是可行的.
- 整合到临床工作流程需要适应有效的实践实施.
- 建议进行进一步的研究,以评估患者长期接受和该计划在改善健康结果方面的有效性.
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