全球CRC循环RNA研究的图书统计和视觉分析 2015-2023年
Jian Feng Bin1, Long Fei Chen2, Yan Wang3
1Department of Gastrointestinal Surgery, The Third Affiliated Hospital of Zunyi Medical University (Zunyi First People's Hospital), Zunyi, China.
Frontiers in immunology
|July 3, 2025
概括
循环RNAs (circRNAs) 显示为结直肠癌 (CRC) 诊断和治疗的生物标志物具有前途. 研究正在转向了解它们的分子机制,以改善CRC管理.
科学领域:
- 在瘤学瘤学.
- 分子生物学分子生物学
- 生物信息学是一种生物信息学.
背景情况:
- 结肠直肠癌 (CRC) 是全球癌症死亡的主要原因.
- 循环RNAs (circRNAs) 是有前途的生物标志物,因为它们的稳定性和存在于体液中.
- circRNAs在CRC细胞增殖,迁移,入侵和亡中发挥作用.
研究的目的:
- 在结直肠癌中进行circRNA研究的文献分析.
- 确定当前的趋势,研究热点和该领域的未来方向.
- 评估circRNA研究对于CRC诊断和治疗的现状.
主要方法:
- 对截至2023年12月31日发表的1048篇论文进行了图书统计分析.
- 使用VOSviewer,CiteSpace,Microsoft Excel和R语言进行数据分析.
- 应用特定的纳入和排除标准来选择纸张.
主要成果:
- 中国在出版物方面处于领先地位;南京医学大学和Kiavash Hushmandi具有影响力.
- 瘤学前沿期刊发表了最多的论文.
- 关键的研究术语包括"信号通路"",转移"",扩散"和"耐药性".
结论:
- 研究重点已经从circRNA生物学转移到分子机制.
- circRNAs具有重要的潜力,可以作为CRC诊断,预后和治疗的生物标志物.
- 未来的研究应该探索circRNA在CRC管理中的作用.
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