系统性硬化症患者疼痛的发生率和严重程度
Sei-Ichiro Motegi1, Mona Uchida-Yamada2, Yoshihito Shima3
1Department of Dermatology, Gunma University Graduate School of Medicine, Maebashi, Japan.
The Journal of dermatology
|July 3, 2025
概括
大多数系统性硬化症患者都会经历明显的疼痛,医生经常低估这种疼痛. 在日本,提高医生对患者疼痛经历的认识对于有效的治疗和管理至关重要.
科学领域:
- 类风湿病学 类风湿病学
- 疼痛医学 医学 疼痛医学
- 患者报告的结果
背景情况:
- 系统性硬化症 (SSc) 是一种慢性自身免疫性疾病,其特点是广泛的炎症,纤维化和血管功能障碍.
- 疼痛是SSc中常见和衰弱的症状,显著影响患者的生活质量.
- 患者和医疗保健提供者之间的疼痛感知差异可能导致疼痛管理不足.
研究的目的:
- 调查系统性硬化症 (SSc) 患者疼痛的患病率和严重程度.
- 为了比较患者和医生对疼痛特征的看法,包括类型,位置和严重程度.
- 为了检查日本医生为SSc患者处方的疼痛治疗模式.
主要方法:
- 一项基于互联网的调查于2023年3月在日本进行.
- 涉及301名SSc患者和129名医生.
- 利用麦吉尔简短形式的疼痛问卷 (SF-MPQ-2) 来评估疼痛的严重程度和特征.
主要成果:
- 96.0%的SSc患者报告经历疼痛,明显高于医生估计的43.4%.
- 中位数SF-MPQ-2得分为47.0,持续疼痛是最严重的类型.
- 医生低估了肌肉,头部和腹部的疼痛;患有分散皮肤SSc (dcSSc) 的患者报告的疼痛比患有有限皮肤SSc (lcSSc) 的患者更严重.
- 常见的疼痛位置包括关节,指尖和雷诺现象 (RP).
- 恶心,失眠或腹与更高的疼痛分数有关.
- 疼痛管理策略包括止痛药 (58.9%),自我护理 (48.8%),皮肤症状治疗 (42.6%),以及转诊到疼痛诊所 (16.3%).
结论:
- 大多数系统性硬化症患者经历了显著的疼痛,这经常被医生低估.
- 患者报告的疼痛和医生的感知之间存在着显著的差距,这突出了改善医生教育和意识的需要.
- 对患者疼痛经历的更好理解对于优化疼痛管理策略和改善SSc患者的治疗结果至关重要.
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