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Updated: Sep 8, 2025

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人类细胞巨乳病毒编码的pUS28通过准CIITA来对抗CD4+T细胞的识别

Fabienne Maassen1,2, Vu Thuy Khanh Le-Trilling1,3, Luisa Betke2

  • 1Institute for Virology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.

eLife
|July 3, 2025
PubMed
概括

人类细胞巨血病毒 (HCMV) 使用其潜伏调节器pUS28来逃避免疫检测. 这种病毒蛋白抑制了人类白细胞抗原II类 (HLA-II) 的表达,阻止了CD4+T细胞的识别,特别是在免疫受损的个体中.

关键词:
CD4+ T 细胞是 CD4+ T 细胞.CD74 CD74 CD74 CD74 CD74 CD74 CD74 CD74 CD74 CD74 CD74 CD74城市 城市 城市G蛋白结合受体的受体是G蛋白结合受体的受体.在GPCR中,GPCR是指GPCR.这就是HCMV.这就是HHV-5的原因.在HLAII类中,HLA是II类.在HLA-DP的基础上.在 HLA-DR 组合下,人类细胞巨型病毒病毒.M3333 没有任何问题.美国28美元人类疹病毒5传染病是一种传染性疾病.延迟时间 延迟时间微生物学的微生物.病毒病毒病毒病毒.

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