在COVID-19后患有艾滋病的患者中,神经与同时出现的加密球菌脑膜炎:一个病例报告
1Department of Infectious Diseases, Huzhou Central Hospital, Affiliated Central Hospital of Huzhou University, Huzhou, China.
Journal of infection in developing countries
|July 3, 2025
概括
患有人类免疫缺陷病毒 (HIV) 和SARS-CoV-2共感染的患者面临严重脑膜炎感染的风险增加. 及时诊断和综合治疗,包括抗逆转录病毒疗法,对于管理这些中枢神经系统并发症至关重要.
科学领域:
- 神经科学是一个神经科学.
- 传染性疾病 传染性疾病
- 免疫学 免疫学 免疫学
背景情况:
- 艾滋病毒患者常见的脑膜炎病原体包括Cryptococcus neoformans和Treponema pallidum.
- 与SARS-CoV-2的同时感染会增加艾滋病毒感染者的脑膜炎风险.
研究的目的:
- 报告与SARS-CoV-2同时感染的HIV患者病例,同时呈现神经和加密球菌脑膜炎.
- 突出在COVID-19大流行期间免疫功能低下个体中中枢神经系统感染的风险增加.
主要方法:
- 一个38岁的男性患有艾滋病毒,SARS-CoV-2,神经和加密球菌脑膜炎的病例介绍.
- 诊断程序包括聚合酶连锁反应测试和腰部穿刺.
- 治疗包括尼尔马特雷尔维尔 - 里托纳维尔,青素,抗真菌和抗逆转录病毒疗法.
主要成果:
- 患者出现头痛和头,诊断为神经和加密球菌脑膜炎.
- 用抗病毒,抗生素,抗真菌和抗逆转录病毒药物的组合成功治疗.
- 患者在6个月的随访期间保持稳定,没有进一步的神经症状.
结论:
- 感染艾滋病毒的患者,特别是那些没有接受抗逆转录病毒治疗的患者,在COVID-19大流行期间面临更高的严重感染风险,包括中枢神经系统并发症.
- 及时诊断和多方面的治疗对于管理共感染和改善免疫受损患者的结果至关重要.
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