抗生素管理计划 (ASP) 的实施比合理使用药物的国家行动计划更有效
Cem Karaali1, Huseyin Esin1, Orhan Ureyen2
1Department of General Surgery, University of Health Sciences Izmir Faculty of Medicine, Tepecik Education and Research Hospital, Yenisehir, Izmir, Turkey.
Journal of infection in developing countries
|July 3, 2025
概括
修改后的抗生素管理计划 (mASP) 和国家合理药物使用行动计划 (NAPRDU) 改善了手术预防 (SP). mASP在SP实践和排放处方方面表现出更快,更有效的改进.
科学领域:
- 传染性疾病 传染性疾病
- 手术护理 手术护理
- 医疗保健服务研究 医疗服务研究
背景情况:
- 抗生素管理计划 (ASP) 对于优化医疗保健环境中的抗生素使用至关重要.
- 手术预防 (SP) 是ASP可以影响抗生素耐药性和患者结果的关键领域.
- 评估不同ASP模型的长期有效性对于基于证据的实践至关重要.
研究的目的:
- 为了比较修改后的抗生素管理计划 (mASP) 与国家合理药物使用行动计划 (NAPRDU) 对外科预防 (SP) 实践的长期影响.
- 评估这些计划对SP在一般外科诊所的出院处方中持续存在的影响.
- 确定哪个计划可以更快,更有效地改善SP.
主要方法:
- 在两个普通外科诊所 (诊所A:mASP,诊所B:NAPRDU) 进行了对SP实践的回顾性检查.
- 使用2013年,2016年,2018年和2023年的季度数据进行横截面比较.
- 分析SP的指示,持续时间,处方中的抗生素使用,以及给药时间.
主要成果:
- 无论是mASP还是NAPRDU,都导致了SP指标,持续时间 (>24小时) 和处方中的抗生素使用的长期显著改善.
- 在SP的所有阶段都观察到改善,除了给药时间 (p < 0.05).
- 与B诊所 (NAPRDU) 相比,使用mASP的A诊所在这些SP参数中显示出明显的更大和更快的改善.
结论:
- 无论mASP还是NAPRDU都会对长期的SP实践和通用外科的处方模式产生积极的影响.
- mASP在改善SP实践方面表现出卓越的有效性和速度,特别是在出院处方中的抗生素方面.
- 这些发现强调了定制的ASP干预措施对优化外科预防的潜在好处.
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