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德黑兰的宫内生长限制及其相关因素,比较3个共同标准

Mahtab Toulany¹, Narjes Khalili¹, Mohammad Heidarzadeh²

¹Preventive Medicine and Public Health Research Centre, Psychosocial Health Research Institute, Department of Community and Family Medicine, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.

|July 3, 2025

概括

根据使用的诊断标准,子宫内生长限制 (IUGR) 的患病率有很大差异,这凸显了全球共识的必要性. 关键的危险因素包括新生儿三症21,母亲成和子宫前.

科学领域:

新生儿科学新生儿科学
公共卫生公共卫生
产科产科产科产科产科

背景情况:

对于在出生时诊断子宫内生长限制 (IUGR) 没有全球共识.
用于IUGR诊断的标准化图表缺乏普遍采用.
评估不同的标准对于准确的流行率估计至关重要.

研究的目的:

使用三个共同标准,比较德黑兰的IUGR流行率.
在研究人群中识别与IUGR相关的因素.
为建立关于IUGR诊断的全球共识提供信息.

主要方法:

利用伊朗母亲和新生儿网络登记处在德黑兰 (2018年) 单胎活产的数据.
用世卫组织,INTERGROWTH-21st和特定人口的图表来定义IUGR为出生体重低于第10百分位.
使用后勤回归来确定与IUGR相关的因素.

主要成果:

IUGR的流行率从4.2% (INTERGROWTH-21st) 到11.8% (WHO) 不同.
新生儿三综合症21,孕产妇成,黄昏症/黄昏前症,慢性高血压,堕胎史,初怀孕,晚期孕产妇年龄和血缘关系与较高的IUGR率有关.
孕产妇妊娠糖尿病,高等教育,私人医院分娩和特定城市居住与较低的IUGR率有关.

结论:

IUGR的流行程度高度依赖于所使用的诊断标准.
对于IUGR诊断标准的全球共识存在重大需要.
新生儿三综合症21,孕产妇成和阴/阴前期表现出与IUGR最强的积极关联.

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