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Updated: Sep 17, 2025

Ganglioside Extraction, Purification and Profiling
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在GM2化酶中,等离子体膜重塑驱动突触功能障碍.

Alex S Nicholson1, David A Priestman2, Robin Antrobus1

  • 1Cambridge Institute for Medical Research, University of Cambridge, Cambridge, United Kingdom.

PLoS biology
|July 3, 2025
PubMed
概括

甘氨基脂 (GSLs) 的积累,就像甘地化物GM2一样,导致神经退行. 这项研究揭示了 lysosomal exocytosis 改变了神经元等离子体膜,影响了质化体的功能.

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