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Updated: Sep 17, 2025

Studying Dynamic Processes of Nano-sized Objects in Liquid using Scanning Transmission Electron Microscopy
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Studying Dynamic Processes of Nano-sized Objects in Liquid using Scanning Transmission Electron Microscopy

Published on: February 5, 2017

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启用液体扫描电子显微镜用于使用真空兼容液体囊的治疗悬浮

Raina Borum1, Paul Reichert2, Zhao Li3

  • 1Analytical Research and Development, Merck & Co., Inc., Rahway, New Jersey 07065, United States.

Analytical chemistry
|July 3, 2025
PubMed
概括

我们增强了液体扫描电子显微镜 (湿SEM) 通过改善样本粘附和对比度来成像治疗悬浮. 这允许对小型有机和生物材料进行高分辨率的实地分析,有助于药物开发.

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Advancing High-Resolution Imaging of Virus Assemblies in Liquid and Ice

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相关概念视频

Preparation of Samples for Electron Microscopy01:20

Preparation of Samples for Electron Microscopy

To be visualized by an electron microscope, either transmission or scanning, biological samples need to be fixed (stabilized) so the electron beam does not destroy them and dried thoroughly (desiccated/dehydrated) so the vacuum does not affect them. Fixation needs to be done as quickly as possible because the sample properties will start changing as soon as it is removed from its natural environment. For example, in a tissue sample, the oxygen levels begin decreasing, causing an altered...
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