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在类风湿性关节炎免疫性突触中STAT3酸化

Hila Novak-Kotzer1, Jesusa Capera2, Ashwin Jainarayanan2

  • 1Skirball Institute of Biomolecular Medicine, NYU Langone Medical Center, New York, NY, 10016, USA; Kennedy Institute of Rheumatology, NDORMS, University of Oxford, Oxford, OX3 7FY, UK.

Journal of autoimmunity
|July 3, 2025
PubMed
概括

发现了一种新的JAK独立途径,通过免疫突触激活T细胞中的STAT3. 这条涉及LCK和TCR的途径在类风湿性关节炎 (RA) 中受损,为耐药患者提供了新的治疗点.

关键词:
CD4 T 细胞是 CD4 的 T 细胞.免疫学的突触.雅克抑制剂的使用在 LCKCK LCK 中.类风湿性关节炎 类风湿性关节炎 类风湿性关节炎在STAT3中,我们可以使用STAT3.

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