通过在粘弹性介质中使用多频超声波信号,研究惯性化值和相应的热和机械效应
Tatiana Filonets1, Maxim Solovchuk2, Chi-Fang Chen3
1Institute of Biomedical Engineering and Nanomedicine, National Health Research Institutes, No. 35, Keyan Road, Zhunan 35053, Taiwan, ROC.
Ultrasonics sonochemistry
|July 3, 2025
概括
多频超声波信号,特别是三频超声波信号,可显著降低惯性化值,并增强热力/机械效应. 最佳频率降低了洞穴压力,扩大了损伤区,有助于集中超声波癌症治疗.
科学领域:
- 声学 声学 在声学方面
- 生物物理学的生物物理.
- 医学物理 医学物理
背景情况:
- 在聚焦超声疗法中,惯性化是至关重要的.
- 了解多频超声波下的化值和影响对于治疗优化至关重要.
研究的目的:
- 通过使用多频超声波,对惯性化值和相关的热力/机械效应进行数值研究.
- 确定最佳频率,以最大限度地减少化值,并最大限度地提高治疗效果.
主要方法:
- 使用吉尔莫模型与线性粘弹性模型相结合,模拟了泡动力学.
- 根据气泡半径膨胀和崩速度标准计算的惯性化值.
- 量化功率沉积和与应变相关的机械损伤.
主要成果:
- 与单频信号相比,多频信号 (双频和三频) 降低了化值.
- 三倍频率信号产生了最低的值和最大的损伤区域 (20-30倍扩大).
- 崩速度标准显示了更高的值,但更快的电力沉积增加和更大的损害区域.
结论:
- 最佳的多频超声波可以有效降低惯性化值.
- 这种方法增强了热和机械效应,潜在地改善了聚焦超声波癌症治疗.
- 结果为优化治疗应用中的超声波参数提供了基础.
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