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利用压电材料用于瘤治疗:目前的进展和前景

Zhengqiao Lyu¹, Weifeng Liu², Chenglong Chen²

¹First Hospital of Shanxi Medical University, Taiyuan 030001, China.

Acta biomaterialia

|July 3, 2025

概括

压电材料将机械能量转化为电场,用于向癌症治疗. 这些先进的材料提供精确的药物输送和动态治疗,最大限度地减少对健康组织的伤害.

科学领域:

生物材料科学生物材料科学
在瘤学瘤学.
纳米技术纳米技术

背景情况:

压电材料为癌症治疗提供了独特的机电联接.
它们将能量 (超声波,机械) 转化为局部电场.
纳米零电材料解决瘤微环境的复杂性,如缺氧和酸度.

研究的目的:

审查瘤治疗中压电材料的分类,机制和治疗应用.
突出它们在多式模式癌症治疗中的作用.
讨论纳米零电材料的进步,以提高效率.

主要方法:

对癌症治疗中的压电材料现有文献的综述.
分析它们的机制,包括能量转换和ROS产生.
探索药物输送和电刺激中的应用.

主要成果:

压电材料可以实现精确的药物输送和增强的反应性氧物种 (ROS) 生产.
它们促进局部电刺激,不影响健康的组织.
纳米零电材料在复杂的瘤微环境中显示出增强的有效性.

结论:

压电材料代表了精确,最少侵入性癌症治疗的有前途的战略.
与纳米技术的整合增强了它们的治疗潜力.
对生物相容性,生物安全性和临床翻译的进一步研究至关重要.

关键词:

压电材料是压电材料.压电瘤治疗疗法压电瘤治疗有反应性氧物种的反应性氧物种.瘤微环境是一个微环境.超声波超声波是指超声波的使用.

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