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Updated: Sep 17, 2025

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开发和应用一个定制的在线亲和力选择质谱选平台

Jun Zhang1, Jerry Barney1, Qingqing Shen1

  • 1Bristol Myers Squibb, Discovery & Development Sciences, 3551 Lawrenceville Princeton Rd, Princeton, NJ 08648, USA.

SLAS technology
|July 3, 2025
PubMed
概括

一个新的在线亲和力选择质谱 (ASMS) 平台提高了药物发现效率. 这个系统提高了速度,减少了假阳性,并使得直接的亲和度排名用于击中优化.

关键词:
亲和度排名 亲和度排名亲和力选择质谱学质谱学.有约束力的选选.高吞吐量选的高吞吐量选击中发现的发现.

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Tandem mass spectrometry, also known as MS/MS or MS2, is an analytical technique that employs two mass analyzers. Essentially it is a series of mass spectrometers that helps isolate a particular biomolecule and then helps study its chemical properties.
This technique helps gather information regarding the protein from which the peptide was obtained and to study the peptides’ amino acid sequence. Identifying peptides from a complex mixture is an important component of the growing field of...
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