婴儿维生素B12状态及其预测因子 - - 一项正在进行的随机对照试验的横截面基线结果
Sol Maja G Bjørkevoll1, Maria O'Keeffe1, Carolien Konijnenberg2
1Department of Pediatric and Adolescent Medicine, Innlandet Hospital Trust, Lillehammer, Norway; Department of Global Public Health and Primary Care, Centre for International Health, University of Bergen, Bergen, Norway.
The American journal of clinical nutrition
|July 3, 2025
概括
许多挪威婴儿表现出低维生素B12状态的生化迹象,特别是那些被母乳养的婴儿. 需要进一步的研究,以了解这些发现在婴儿早期的临床意义.
科学领域:
- 儿童营养学 儿童营养学
- 生物化学 生物化学
- 公共卫生 公共卫生
背景情况:
- 维生素B12对于婴儿发育至关重要.
- 评估婴儿的维生素B12状况对于早期干预至关重要.
- 维生素B12状态的生物标志物截止值通常基于成人数据.
研究的目的:
- 为了评估6-15周岁的挪威婴儿的维生素B12状态.
- 用多种生物标志物和切断方法进行综合评估.
- 在这个婴儿群体中确定维生素B12状态的预测因子.
主要方法:
- 在挪威招募了644名婴儿 (年龄在6-15周) 和他们的母亲.
- 分析了血中的可巴胺,甲基马龙酸 (MMA) 和总同型半氨酸 (tHcy) 度.
- 计算了一个综合指标 (cB12),并应用了各种切断方法来确定维生素B12状态.
主要成果:
- 很大一部分婴儿表现出低维生素B12状态的生化指标.
- 与非母乳养的婴儿相比,完全或部分母乳养的婴儿显示出较低的维生素B12状态.
- 特定的生物标志物度表明了潜在的缺陷,在不同的切线上有不同的百分比.
结论:
- 许多挪威婴儿表现出生物化学征兆,表明维生素B12水平较低.
- 哺乳状态与较低的维生素B12生物标志物水平有关.
- 这些发现的临床影响需要在婴儿早期进一步调查.
关键词:
维生素B12是一种维生素.母乳养 母乳养 哺乳cB12 这是一个很好的例子.科巴拉胺是什么意思同型半氨酸同型半氨酸婴儿 婴儿 婴儿 婴儿 婴儿甲基马龙酸是一种甲基马龙酸.微量营养素是一种微量营养素.更多相关视频
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