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通过Streptococcus thermophilus TCI633补充剂进行肠乳轴调节:对母婴微生物组动态的研究

C-C Chen¹, T-Y Lin², W-K Wu^3,4

¹Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.

Beneficial microbes

|July 3, 2025

概括

母亲补充益生菌可能通过母乳传递给婴儿,可能会影响婴儿肠道微生物群. 这项研究探讨了S. thermophilus TCI633传播和婴儿殖民的肠-乳房轴.

科学领域:

微生物学微生物学
免疫学免疫学免疫学
人类微生物组研究研究

背景情况:

母乳含有益生菌,对婴儿肠道微生物群和免疫发育至关重要.
肠-乳腺轴理论认为,母亲的肠道微生物群通过免疫信号影响母乳成分.

研究的目的:

为了研究婴儿肠道中Streptococcus thermophilus TCI633的殖民潜力.
探索S. thermophilus TCI633通过肠-乳房轴的转移.

主要方法:

研究了30对纯母乳养的母婴对.
母亲每天接受S. thermophilus TCI633在出院后的一个月.
分析了母乳,母体便和婴儿便的微生物群和TCI633的存在.

主要成果:

观察到母乳和便微生物群的轻微变化.
发现S. thermophilus的数量略有增加.
在66.7%的婴儿便样本中检测到TCI633特异性的基因片段.

结论:

初步证据表明,S. thermophilus TCI633可以通过肠-乳房轴传播.
婴儿肠道被TCI633殖民是可行的,但功能意义需要进一步调查.

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