跨导管中枢替换的SAPIEN M3系统:一个新的时代开始了
Michail Penteris1, Konstantinos Lampropoulos2
1Department of Medicine, Democritus University of Thrace, Alexandroupolis, Greece.
概括
使用SAPIEN M3系统进行过导管 mitra 置换 (TMVR) 对患有 mitra 吐的高风险患者显示出有前途. 早期的研究表明,高成功和有效的MR减少,正在进行试验,以评估长期结果.
科学领域:
- 心血管医学 心血管医学
- 干预心脏病学 干预心脏病学
- 医疗器械 医疗器械
背景情况:
- 副心脏反 (MR) 是一种常见的,未得到充分治疗的膜心脏病,特别是在手术风险高的患者中.
- 过导管中枢门修复 (M-TEER) 有局限性,推动过导管中枢门更换 (TMVR) 技术的创新.
研究的目的:
- 为了评估新的SAPIEN M3系统,一个全皮穿透导管中枢替换技术.
- 评估SAPIEN M3系统的可行性,安全性和有效性,用于患有MR手术风险过高的患者.
主要方法:
- SAPIEN M3系统具有两部分的设计:一个尼醇接头和一个适用于中的SAPIEN 3门.
- 这种方法旨在稳定定,最大限度地减少左心室外流通道 (LVOT) 的阻塞,并且独立于环状化.
主要成果:
- 早期可行性研究报告的技术成功率超过85%.
- 该系统证明有效地减少了额头肌吐,并在高风险人群中显示出良好的安全性.
- 目前正在进行的试验,如ENCIRCLE,将进一步调查安全性和长期结果.
结论:
- 在高风险的MR患者中,SAPIEN M3系统代表了一种有前途的新型TMVR方法.
- 虽然早期结果令人鼓舞,但需要进一步评估程序复杂性,LVOT阻塞和长期耐用性.
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