单个抗生素及其混合物在环境相关的度可能会扰乱A. obliquus的生理学
Marta Galas1, Marta Grabska2, Maksymilian Zienkiewicz3
1Department of Biochemistry and Microbiology, Institute of Biology, Warsaw University of Life Sciences (SGGW), Nowoursynowska, 159, 02-776, Warsaw, Poland. marta_galas@sggw.edu.pl.
Scientific reports
|July 3, 2025
概括
淡水中的抗生素会伤害绿藻Acutodesmus obliquus. 即使在低水平下,这些污染物,包括氨基醇和链杆菌素,也会破坏藻类的生长和生理学,混合作用是显著的.
科学领域:
- 环境科学 环境科学
- 生态毒理学 生态毒理学
- 藻类生物学 藻类生物学
背景情况:
- 抗生素是普遍存在的淡水污染物.
- 非目标生物,如初级生产者 (绿藻),面临风险.
- 了解抗生素对藻类的影响对于生态系统健康至关重要.
研究的目的:
- 为了研究氨基醇,菌素,硫甲和它们的混合物对绿色藻类Acutodesmus obliquus的影响.
- 评估长时间 (10天) 暴露于环境相关的抗生素度后的生理反应.
- 评估抗生素混合物对藻类生理学的潜在累积影响.
主要方法:
- 对单个抗生素 (氨基醇,菌素,硫甲) 和它们的混合物暴露的Acutodesmus obliquus
- 环境相关度的应用 (ng L-1范围).
- 在10天后测量藻类生长速度,细胞大小,叶绿素,胡卜素,光,呼吸和脂质过氧化.
主要成果:
- 氨基醇降低了生长速度,细胞大小和最大光度的变量.
- 硫甲醇降低了生长速度,细胞大小,叶绿素和胡卜素.
- 抗生素混合物显著影响了生长速度,细胞大小,叶绿素a,叶绿素a/b比率,增加了呼吸,表明累积效应.
结论:
- 环境相关的抗生素度对Acutodesmus obliquus生理学产生负面影响.
- 与单个化合物相比,抗生素混合物表现出更广泛的不良影响.
- 这项研究强调了制药污染物在淡水生态系统中的累积生态毒理学影响的潜力.
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