传统香烟和电子香烟使用对精子质量和IVF/ICSI结果的影响
Hye Kyeong Kim1, Won Yun Choi2, Jin Il Lee2
1Department of Obstetrics and Gynecology, CHA University Ilsan Medical Center, CHA University School of Medicine, Goyang, Gyeonggi-do, Korea.
Scientific reports
|July 3, 2025
概括
与传统吸烟相比,在接受体外受精 (IVF) 的男性伴侣中,电子烟使用与更高的活产率有关. 电子烟使用者也表现出精子运动能力的改善,这表明男性生育能力的危害可能减少.
科学领域:
- 生殖医学 生殖医学
- 男人的健康 男人的健康
- 戒烟的替代方法 戒烟的替代方法
背景情况:
- 电子烟 (E-cigarettes) 是传统吸烟的替代品,含有较少有害物质.
- 尽管危害减少了,但电子烟仍然可能对健康构成风险.
- 电子烟使用对男性生育能力和体外受精 (IVF) 结果的影响需要调查.
研究的目的:
- 追溯分析传统香烟和电子香烟吸烟对男性试管婴儿结果的影响.
- 为了比较传统吸烟者,电子烟使用者和潜在的对照组 (尽管没有明确说明) 之间的关键生育和怀孕指标.
主要方法:
- 对151名常规香烟吸烟者和145名电子香烟吸烟者进行试管婴儿 (2022年5月 - 2024年1月) 的回顾性分析.
- 不孕不育的原因包括输卵管因素,PCOS,甲状腺功能障碍和高甲状腺性血.
- 主要结局:卵细胞检索,二核子 (2PN) 胚胎,受精,植入,正在进行的怀孕和活产率. 二次结果:精液参数.
主要成果:
- 与传统香烟组相比,电子香烟组的活产率明显高 (p=0.011).
- 电子烟使用者表现出显著降低基底血清益乳素水平 (p=0.029) 和改善精子运动性 (p=0.014).
- 男性的BMI,FSH水平,平价和2PN胚胎数量是活产的重要预测因素;FSH和2PN胚胎数量是独立的因素.
结论:
- 电子烟可能对男性生育指标,特别是精子运动性不如传统香烟那么有害.
- 这些发现表明,电子烟使用对接受试管婴儿治疗的男性伴侣的活产率比传统吸烟有潜在的好处.
- 需要进一步的研究来证实电子烟在生殖环境中的长期影响和安全性.
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