维生素B2摄入量与女性不孕症之间的关联:一个横截面研究
Zitong Zhao1, Zenghui Mao1, Min Liu1
1Center of Reproductive Medicine, Hunan Provincial Key Laboratory of Regional Hereditary Birth Defects Prevention and Control, Changsha Hospital for Maternal and Child Health Care Affiliated to Hunan Normal University, Changsha, 410007, P R China.
Scientific reports
|July 3, 2025
概括
较高的维生素B2摄入量与较低的女性不孕症风险有关. 足够的 рибофлавин (维生素B2) 水平可能对妇女的生殖健康和预防不孕症很重要.
科学领域:
- 营养科学 营养科学
- 生殖健康 生殖健康
- 公共卫生 公共卫生
背景情况:
- 无法解释的女性不孕症给公共卫生和心理健康带来了重大挑战.
- 对影响不孕不育的饮食因素的研究往往忽视了维生素B2 ( рибофлавин) 的作用.
研究的目的:
- 调查维生素B2摄入量与女性不孕症患病率之间的关联.
- 探索维生素B2作为治疗女性不孕症的可修改因素的潜力.
主要方法:
- 使用国家健康和营养检查调查 (NHANES) 数据 (2013-2018) 的横截面研究.
- 进行了多变量逻辑回归分析和子组分析.
- 限制立方线 (RCS) 用于评估线性趋势.
主要成果:
- 总共有3,208名妇女被分析,其中524名被确定为不育.
- 增加的维生素B2摄入量与女性不孕症的较低患病率显著相关 (OR [95% CI]:0.81 [0.69,0.96]).
- 与最低四分位数相比,维生素B2摄入的最高四分位数显示出保护作用 (OR [95% CI]:0.58 [0.38,0.89]).
结论:
- 更高的维生素B2摄入量与女性不孕症风险降低有关.
- 通过饮食或补充剂维持足够的 рибофлавин水平可能是预防和管理不孕症的策略.
- 观察到的关联在各种人口学子组中是一致的.
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