在患有二次白血病的患者中,对18F-FDG PET/CT进行肝脏超扫描
Ali Gümüş1, Merve Nida Calderon Tobar, Gonca Kara Gedik
1Department of Nuclear Medicine, Faculty of Medicine, Selcuk University, Konya, Turkey.
Clinical nuclear medicine
|July 4, 2025
概括
一名患者被诊断患有二次白血病,这是一种已知的癌症治疗的副作用,如布伦图西马布维多丁. 图像检查显示肝脏异常,活检证实是急性髓性白血病 (AML).
科学领域:
- 在瘤学瘤学.
- 血液学 血液学 血液学
- 医疗成像医学成像
背景情况:
- 二次性白血病是化疗和放射治疗后的一种已知的并发症.
- 布伦图西马布维多丁是一种用于霍奇金淋巴瘤的向治疗.
- 早期发现与治疗相关的并发症对于患者管理至关重要.
研究的目的:
- 报告二次急性髓性白血病 (AML) 的病例,该病例是在Brentuximab vedotin治疗霍奇金淋巴瘤后出现的.
- 突出18F-FDG PET/CT在诊断治疗相关并发症中的作用.
- 讨论二次AML的临床表现和诊断途径.
主要方法:
- 一名61岁的患有混合型霍奇金淋巴瘤的男性患者于2021年接受了布伦图西马布维多丁.
- 诊断工作包括18F-FDG PET/CT扫描,因为出现了症状.
- 骨髓活检进行,以确定确诊.
主要成果:
- 18F-FDG PET/CT扫描揭示了肝扩大和扩散性增加了肝脏中的FDG吸收,与肝脏超级扫描一致.
- 骨髓活检证实了急性髓性白血病 (AML) 的诊断.
- 该患者在霍奇金淋巴瘤诊断时无症状,但出现导致AML检测的症状.
结论:
- 二次性AML可能是布伦图西马布维多丁治疗的晚期并发症.
- 18F-FDG PET/CT可以成为识别二次白血病肝脏参与的一个有价值的工具.
- 通过骨髓活检及时诊断对于管理与治疗相关的骨髓瘤至关重要.
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