跨导管大动脉门的长期耐用性在双侧大动脉狭窄症患者中
Yuheng Jia1,2, Annette Maznyczka3, Mauro Boiago4
1The Heart Center, Rigshospitalet, Copenhagen, Denmark.
概括
跨导管大动脉 (TAVs) 在双管大动脉狭窄症 (AS) 患者中显示出良好的5年耐用性. 年轻的患者可能需要重新干预,正确的TAV大小对于更好的结果至关重要.
科学领域:
- 心脏病学 心脏病学
- 干预心脏病学 干预心脏病学
- 生物材料科学 生物材料科学
背景情况:
- 有限的数据存在于跨导管大动脉 (TAV) 的长期耐用性,特别是在双大动脉狭窄 (AS) 的患者中.
- 了解这一群体的TAV耐用性对于优化治疗策略至关重要.
研究的目的:
- 在被诊断患有双性AS的患者中,通过导管进行大动脉置换 (TAVR) 后报告长期门耐用性.
- 评估影响门耐用性和重新干预率的因素.
主要方法:
- 一项多中心注册研究,涉及患者接受TAVR治疗双骨AS.
- 需要至少2年的心声学随访.
- 结构恶化 (SVD),生物假体功能障碍 (BVD) 和生物假体故障 (BVF) 被使用学术研究联盟 (VARC) -3标准评估.
主要成果:
- 在894名患者中,中度至重度SVD,重度SVD,重度BVD和BVF的5年累计发病率分别为8.1%,3.2%,11.4%和6.1%.
- 年龄较小 (≤75岁) 和TAV缩小与更高的再干预率,SVD,BVD和BVF有关.
- 在患有小环形的患者中,气球可扩展的TAV与自我扩展的TAV相比,显示出更高的BVD率.
结论:
- 跨导管大动脉在患有双骨AS的患者中表现出良好的5年耐用性.
- 年轻的患者可能更有可能需要重新进行门干预.
- 标称TAV尺寸和小型环形自扩展与更好的耐用性和血液动力学结果有关.
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