结构性和功能性注意力网络连接性与大脑视觉障碍中的视觉选择性注意力功能障碍有关
Marie Drottar1, Claire E Manley2, Negin Nadvar1
1Laboratory of Neuroimaging and Vision Science, Department of Radiology, Massachusetts General Hospital, 125 Nashua Street, Boston, MA 02114, United States.
Cerebral cortex (New York, N.Y. : 1991)
|July 4, 2025
概括
大脑视力障碍 (CVI) 患者在视觉注意力任务中表现出大脑连接的改变. 在CVI中视觉搜索受损与较弱的结构和更强的功能连接有关,这表明存在补偿机制.
科学领域:
- 神经科学是一个神经科学.
- 眼科医生 眼科 眼科
- 认知科学 认知科学
背景情况:
- 大脑视力障碍 (CVI) 通常涉及视觉选择性注意力的困难.
- 在CVI中引起这些注意力缺陷的神经支尚未得到充分理解.
研究的目的:
- 研究与对照人群相比,CVI患者的结构性和功能性大脑连接和视觉搜索性能之间的关系.
- 探索注意力网络,丘脑和早期视觉区域在CVI相关的视觉注意力缺陷中的作用.
主要方法:
- 神经成像 (结构和功能连接) 和行为数据从26名参与者 (10名CVI,16名对照) 中收集.
- 为背部和腹部注意力网络生成了白质道和连接矩阵.
- 一般线性模型分析了神经成像变量与连接搜索任务性能之间的关联,控制年龄和语言认知.
主要成果:
- 在CVI组中,视觉搜索受损与结构连接性较弱和功能连接性较强相关.
- 在对照组中,观察到相反的模式:更好的视觉搜索与更强的结构和较弱的功能连接有关.
- 这些发现突出了连接性和视觉搜索之间的关系中的群体差异.
结论:
- 改变的大脑连接模式与CVI中的视觉注意力缺陷有关.
- 在CVI中更强的功能连接可能代表视觉处理受损的不适应性补偿机制.
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