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一个神经经济理论的强迫症障碍
Anıl Şafak Kaçar1,2, Ahmed A Moustafa3,4, Mubashir Hassan5
1Department of Psychology and Research Center for Translational Medicine, Koç University, Istanbul, Turkey.
强迫症 (OCD) 可能源于对认知控制成本的高估,由忽视强迫症带来的情感负担驱动. 这种神经经济模型解释了强迫行为是受欢迎的自动反应.
科学领域:
- 神经科学是一个神经科学.
- 计算精神病学是一种计算精神病学.
- 神经经济学 神经经济学
背景情况:
- 强迫症 (OCD) 缺乏一个统一的神经计算框架.
- 现有的研究重点是神经相关物,而不是一个连贯的理论模型.
研究的目的:
- 建议使用预期控制值 (EVC) 理论,为强迫症提出一个神经计算框架.
- 通过信息处理缺陷来解释强迫症症状,特别是强迫症和强迫症.
主要方法:
- 在EVC框架内对强迫症症状进行概念化.
- 将EVC组成部分与涉及强迫症的神经系统联系起来 (例如OFC,dACC,dlPFC,基底).
- 整合从striata terminalis的床核到dACC的情感成本计算.
主要成果:
- 在痴迷期间,由于忽视引起焦虑的想法所带来的情感代价,认知控制较弱是有利的.
- 这导致了对认知控制成本的高估,促进了强迫行为.
- 该框架可以容纳各种强迫症症状表现.
结论:
- EVC理论为强迫症的信息处理缺陷提供了一个神经经济学上的解释.
- 影响性成本,特别是从BNST到dACC,对于对强迫症患者的EVC估计至关重要.
- 这一框架为强迫症背后的神经机制提供了新的视角.
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