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Updated: Sep 17, 2025

Chemical Inactivation of the E3 Ubiquitin Ligase Cereblon by Pomalidomide-based Homo-PROTACs
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一种新型的大脑变体,在新诊断的和复发的多发性骨髓瘤中,具有8号和10号外因子的删除

Yuan Xiao Zhu1, Soumya Dutta2, Gregory J Ahmann3

  • 1Department of Laboratory Medicine and Pathology, Mayo Clinic Arizona, Phoenix, AZ.

Blood neoplasia
|July 4, 2025
PubMed
概括

多发性骨髓瘤 (MM) 的耐药性是一个挑战. 研究人员开发了一种新方法来检测与耐药性相关的特定CRBN基因变异,甚至在诊断时发现它存在.

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