多囊性卵巢综合征和甲状腺功能低下中的心力衰竭:回顾性大数据库分析
Evidence E Ohikhuai1, Ngozi T Akueme2, Seye Olaniyi3
1Public Health, Jackson State University School of Public Health, Jackson, USA.
Cureus
|July 4, 2025
概括
患有甲状腺功能低下症的多囊性卵巢综合征 (PCOS) 会增加心力衰竭,慢性病,2型糖尿病和高脂血症的风险. 早期查和管理对于这一高风险患者群体至关重要.
科学领域:
- 内分泌学 在内分泌学.
- 心脏病学 心脏病学
- 生殖健康 生殖健康
背景情况:
- 多囊性卵巢综合征 (PCOS) 与代谢综合征风险有关.
- 在PCOS患者中同时出现甲状腺功能低下症可能会显著增加心血管风险.
- 关于PCOS患者心血管结果的数据有限.
研究的目的:
- 为了研究PCOS患者的心血管结果.
- 为了比较PCOS患者和没有甲状腺功能低下症之间的结果.
主要方法:
- 使用了国家住院患者样本数据库 (2016-2020).
- 选择了被诊断为PCOS的患者,并根据甲状腺功能低下的存在对其进行了分层.
- 应用多变量逻辑回归来分析初级 (死亡率) 和二次结果 (高频,T2DM,CKD,中风,HTN,HLD,DVT).
主要成果:
- 分析了78470例PCOS住院病例,14.6%患有甲状腺功能低下症.
- 两组之间死亡率,高血压,中风或DVT没有显著差异.
- 甲状腺功能低下症PCOS患者患心力衰竭 (OR: 1.2),CKD (OR: 1.2),T2DM (OR: 1.2),和HLD (OR: 1.2) 的可能性更高.
结论:
- 在PCOS患者中同时出现的甲状腺功能低下与心力衰竭,CKD,T2DM和HLD的风险增加有关.
- 表明需要对这一群体进行风险分层,查和密切管理.
- 通过积极的医疗保健干预措施,突出了改善结果的潜力.
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