概括
酸是果仁果皮液的成分,是安全的动物料. 日本食品安全委员会发现,它作为料添加剂的使用对人类健康没有危害.
科学领域:
- 食品安全 食品安全
- 动物营养 动物营养
- 毒理学 毒理学 毒理学
背景情况:
- 坚果液 (CNSL) 含有无心酸,一种基,可以减少牛的甲产量.
- 在日本,CNSL被提议被指定为一种新的料添加剂.
研究的目的:
- 进行对使用酸作为料添加剂的风险评估.
- 评估心酸在动物料中的安全性以及对人类健康的潜在影响.
主要方法:
- 基于提交的料添加剂指定数据的风险评估.
- 评估包括动物命运,组织残留,基因毒性,急性毒性和亚急性毒性研究.
- 对于雄性和雌性小鼠,确定未观察到的不良影响水平 (NOAEL).
主要成果:
- 妇女的NOAEL为600 mg/kg bw/day,男性的NOAEL为1000 mg/kg bw/day.
- 虽然没有慢性研究,但亚急性毒性数据和长期食用果仁表明,对慢性影响的担忧很小.
- 自2012年以来,亚纳卡丁酸已在日本作为料成分使用,没有报告牲畜或产品的安全问题.
结论:
- 酸被认为是安全的作为料添加剂.
- 在按照指示使用时,预计食品中的心酸残留不会对人类健康产生不良影响.
- 风险评估支持将含有酸的CNSL指定为安全的料添加剂.
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