在患有非结核性真菌菌菌病的患者中,药物坚持
Arthur Lemson1, Fleur Dijkhuizen1, Ralf Stemkens2
1Department of Pulmonary Diseases, Research Institute for Medical Innovation, Radboud University Medical Center, Nijmegen, the Netherlands.
概括
在治疗的第一年,非结核性真菌菌菌病 (NTM) 患者的药物坚持率很高. 这种坚持与治疗和定期临床随访的必要性有关.
科学领域:
- 传染性疾病 传染性疾病
- 药理学 药理学是指药理学的学科.
- 公共卫生 公共卫生
背景情况:
- 非结核性真菌菌菌 (NTM) 疾病需要长期的抗真菌菌治疗.
- 药物坚持对于NTM疾病等慢性感染的治疗成功至关重要.
- 了解影响坚持的因素对于优化患者的治疗结果至关重要.
研究的目的:
- 测量和理解诊断为NTM疾病的患者的药物坚持.
- 通过客观措施 (覆盖日数比例) 和自我报告尺度 (MARS-5) 评估遵守情况.
- 使用药物问卷 (BMQ) 探索患者对药物的信仰.
主要方法:
- 纳入了正在接受治疗的NTM疾病的成年患者.
- 使用6个月和12个月的覆盖日比例 (PDC) 评估了药物坚持.
- 用5项药物坚持报告尺度 (MARS-5) 和BMQ来评估坚持和信念.
主要成果:
- 观察到很高的坚持,在6个月和12个月的PDC中位数为100%.
- 马尔斯5得分一直保持在高位,这表明自我报告的遵守率很好.
- 患者对NTM治疗的必要性的信念超过了对药物的担忧.
结论:
- 在NTM治疗的第一年,药物坚持率仍然很高.
- 感知到治疗的必要性和定期的临床随访可能有助于高坚持率.
- 这些发现强调了患者教育和支持在管理NTM疾病方面的重要性.
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